Comparison of arterial input functions measured from ultra-fast dynamic contrast enhanced MRI and dynamic contrast enhanced computed tomography in prostate cancer patients
نویسندگان
چکیده
منابع مشابه
Toward local arterial input functions in dynamic contrast-enhanced MRI.
PURPOSE To present a method for estimating the local arterial input function (AIF) within a dynamic contrast-enhanced MRI scan, based on the alternating minimization with model (AMM) method. MATERIALS AND METHODS This method clusters a subset of data into representative curves, which are then input to the AMM algorithm to return a parameterized AIF and pharmacokinetic parameters. Computer sim...
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Introduction The accuracy in pharmacokinetic parameters derived from Dynamic Contrast-Enhanced MRI (DCE-MRI) depends strongly on the quality of the arterial input function (AIF). The AIF is challenging to measure accurately for several reasons. For example, T1 needs to be determined with a temporal resolution of about one second and with a spatial resolution high enough to resolve the artery wh...
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Dynamic contrast-enhanced MRI has been proven to be a valuable technique in cancer imaging. The poorly formed and leaky vessels formed during angiogenesis to supply tumors facilitate an increased uptake of intravenously administered contrast agents in comparison to normal vasculature. The use of mathematical modeling techniques on the change in tumor signal intensity as a function of time provi...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2018
ISSN: 0031-9155,1361-6560
DOI: 10.1088/1361-6560/aaa51b